Synthesis of 2-methyl-4-selenoquinazolone, 2-phenylbenzoselenazole, and its derivatives Dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Faculty of Pure Science of Columbia University

"Synthesis of 2-methyl-4-selenoquinazolone, 2-phenylbenzoselenazole, and Its Derivatives" by Yü-Gwan Chen is an early 20th-century scientific deep dive into the creation and study of selenium-based organic molecules, suggesting their roles in medicine and coloring. The work investigates the creation of new selenium compounds to find out what they do and how they could be used. The dissertation shares the step-by-step process of making 2-methyl-4-selenoquinazolone and 2-phenylbenzoselenazole, along with related variations. Chen walks through the lab techniques used to synthesize these compounds, carefully looking at their characteristics, revealing both their coloring abilities and potential health-related benefits. The research leads to the possibility that these selenium compounds have special coloring features and could be helpful in treating diseases. The dissertation builds the findings on previous studies.